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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1989-4-3
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pubmed:abstractText |
The purpose of this study was to determine if a single dose of radiation to the rat abdomen leads to bacterial translocation into the mesenteric lymph nodes (MLN). A second issue addressed was whether translocation correlates with anatomic damage to the mucosa. The radiated group (1100 cGy) which received anesthesia also was compared with a control group and a third group which received anesthesia alone but no abdominal radiation. Abdominal radiation lead to 100% positive cultures of MLN between 12 hr and 4 days postradiation. Bacterial translocation was almost nonexistent in the control and anesthesia group. Signs of inflammation and ulceration of the intestinal mucosa were not seen until Day 3 postradiation. Mucosal damage was maximal by Day 4. Bacterial translocation onto the MLN after a single dose of abdominal radiation was not apparently dependent on anatomical, histologic damage of the mucosa.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-4804
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2918713-Abdomen,
pubmed-meshheading:2918713-Anesthesia,
pubmed-meshheading:2918713-Animals,
pubmed-meshheading:2918713-Bacteria,
pubmed-meshheading:2918713-Bacterial Physiological Phenomena,
pubmed-meshheading:2918713-Female,
pubmed-meshheading:2918713-Intestinal Mucosa,
pubmed-meshheading:2918713-Intestines,
pubmed-meshheading:2918713-Lymph Nodes,
pubmed-meshheading:2918713-Mesentery,
pubmed-meshheading:2918713-Rats,
pubmed-meshheading:2918713-Rats, Inbred Strains,
pubmed-meshheading:2918713-Time Factors
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pubmed:year |
1989
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pubmed:articleTitle |
Abdominal radiation causes bacterial translocation.
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pubmed:affiliation |
University of Minnesota Medical School, Minneapolis 55455.
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pubmed:publicationType |
Journal Article
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