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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1989-4-3
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pubmed:databankReference | |
pubmed:abstractText |
Two cDNA clones were isolated, one corresponding to the mRNA coding for lactate dehydrogenase-M (LDH-M), the other to the mRNA coding for lactate dehydrogenase-H (LDH-H). The cDNA inserts consist of the entire open reading frame for LDH-M and a partial sequence, from amino acid 117 to 332, for LDH-H. Using these two clones as probes we demonstrate that: (a) the abundance of mRNA is muscle-type dependent; (b) the ratio M/H subunit for protein and mRNA is well related in the muscles studied; and (c) the M + H mRNA level is not relative to the total LDH activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0021-9258
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
|
pubmed:volume |
264
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4076-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2917988-Amino Acid Sequence,
pubmed-meshheading:2917988-Animals,
pubmed-meshheading:2917988-Base Sequence,
pubmed-meshheading:2917988-Blotting, Northern,
pubmed-meshheading:2917988-DNA,
pubmed-meshheading:2917988-Gene Expression Regulation,
pubmed-meshheading:2917988-L-Lactate Dehydrogenase,
pubmed-meshheading:2917988-Molecular Sequence Data,
pubmed-meshheading:2917988-Muscles,
pubmed-meshheading:2917988-Rabbits,
pubmed-meshheading:2917988-Restriction Mapping
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pubmed:year |
1989
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pubmed:articleTitle |
Characterization of rabbit lactate dehydrogenase-M and lactate dehydrogenase-H cDNAs. Control of lactate dehydrogenase expression in rabbit muscle.
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pubmed:affiliation |
Laboratoire de Biochimie, Universite Blaise Pascal-Clermont-Ferrand, Aubiere, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|