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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1989-4-3
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pubmed:abstractText |
This paper describes properties of 86Rb+ fluxes through a novel K+ channel in luminal-membrane vesicles isolated from pars convoluta of rabbit proximal tubule. The uptake of 86Rb+ into potassium salt loaded vesicles was specifically inhibited by Ba2+. The isotope accumulation is driven by an electrical diffusion potential as shown in experiments using these membrane vesicles loaded with anions of different membrane permeability and was as follows: gluconate greater than SO4(2-) greater than Cl-. Furthermore, the vesicles containing the channels show a cation selectivity with the order K+ greater than Rb+ greater than Li+ greater than Na+ = choline+.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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|
pubmed:issn |
0014-5793
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
30
|
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pubmed:volume |
243
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2917644-Animals,
pubmed-meshheading:2917644-Anions,
pubmed-meshheading:2917644-Barium,
pubmed-meshheading:2917644-Cations,
pubmed-meshheading:2917644-Electrophysiology,
pubmed-meshheading:2917644-Kidney Tubules, Proximal,
pubmed-meshheading:2917644-Ouabain,
pubmed-meshheading:2917644-Permeability,
pubmed-meshheading:2917644-Potassium Channels,
pubmed-meshheading:2917644-Rabbits,
pubmed-meshheading:2917644-Rubidium Radioisotopes
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pubmed:year |
1989
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pubmed:articleTitle |
Ba2+-sensitive K+ channels in luminal-membrane vesicles from pars convoluta of rabbit proximal tubule.
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pubmed:affiliation |
Institute of Medical Biochemistry, University of Aarhus, Denmark.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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