| pubmed-article:2915604 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0376604 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0007412 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0027930 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0031621 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0205753 | lld:lifeskim |
| pubmed-article:2915604 | lifeskim:mentions | umls-concept:C0001721 | lld:lifeskim |
| pubmed-article:2915604 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2915604 | pubmed:dateCreated | 1989-3-17 | lld:pubmed |
| pubmed-article:2915604 | pubmed:abstractText | Bovine adrenal medullary cells released significant amounts of opioid pentapeptides Met- and Leu-enkephalin and catecholamines, when stimulated by neurotensin (NT). Maximal release induced by this peptide was about 40-50% of that seen after nicotinic activation of cholinergic receptors. Dose-response curves for neurotensin-induced secretion revealed an EC50 of 1x10(-6)M, thereby being in the range of that for acetylcholine or nicotine. Secretory effects were dependent on extracellular Ca++ and impaired by the Ca++ channel blocker D 600. Moreover NT produced an increase in opioid peptide cell content after 48 and 72 hrs of incubation. Besides affecting opioid peptide metabolism, NT significantly produced accumulation of inositol- 1-phosphates (IP1), the significance of which remains to be clarified in the observed metabolic effects. | lld:pubmed |
| pubmed-article:2915604 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2915604 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2915604 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2915604 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:2915604 | pubmed:author | pubmed-author:HerzAA | lld:pubmed |
| pubmed-article:2915604 | pubmed:author | pubmed-author:BommesLL | lld:pubmed |
| pubmed-article:2915604 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2915604 | pubmed:volume | 44 | lld:pubmed |
| pubmed-article:2915604 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2915604 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2915604 | pubmed:pagination | 327-35 | lld:pubmed |
| pubmed-article:2915604 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:meshHeading | pubmed-meshheading:2915604-... | lld:pubmed |
| pubmed-article:2915604 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2915604 | pubmed:articleTitle | Neurotensin affects metabolism of opioid peptides, catecholamines and inositol phospholipids in bovine chromaffin cells. | lld:pubmed |
| pubmed-article:2915604 | pubmed:affiliation | Department of Neuropharmacology, Max-Planck-Institut für Psychiatrie, Martinsried, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:2915604 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2915604 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2915604 | lld:pubmed |
