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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-3-21
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pubmed:abstractText |
The intravascular (iv) or intramuscular (im) inoculations of a suspension of Lewis carcinoma cells induced metastatic tumor nodules in the lungs of C57Bl/6 mice. The administration of curantil (dipyridamole) (500 mg per 20 g-mouse, per os) once a week beginning one day after iv tumor cells inoculation (2 X 10(5) cells) reduced 4-fold the number of tumor nodules. The administration of curantil one day after im tumor cells inoculation (2 X 10(6) cells) reduced 2-fold the number of tumor nodules. The combined treatment of curantil (4-, 10-days after inoculation) and well-known inducer of interferon poly I:poly C (50 mg per 20 g-mouse, 1-, 7-, 14-days after inoculation tumor cells) had no synergistic effect.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0365-9615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
107
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
83-5
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:2914179-Animals,
pubmed-meshheading:2914179-Dipyridamole,
pubmed-meshheading:2914179-Drug Evaluation,
pubmed-meshheading:2914179-Female,
pubmed-meshheading:2914179-Interferon Inducers,
pubmed-meshheading:2914179-Mice,
pubmed-meshheading:2914179-Mice, Inbred C57BL,
pubmed-meshheading:2914179-Neoplasm Metastasis,
pubmed-meshheading:2914179-Poly I-C,
pubmed-meshheading:2914179-Time Factors
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pubmed:year |
1989
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pubmed:articleTitle |
[Suppression of Lewis carcinoma metastasis in mice by an interferon-inducing vasodilator curantil].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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