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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1989-3-9
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pubmed:abstractText |
Peripheral eosinophil counts were measured at intervals before and after control and allergen inhalation in 14 asthmatic subjects. A relative fall in eosinophil counts was noted 9 h after allergen challenge, in contrast to the diurnal increase seen on the control day (p = 0.005). This fall in eosinophil count correlated strongly with the magnitude of the late asthmatic response (r = -0.72, p = 0.003) and with the changes in bronchial responsiveness to histamine at 3 and 24 h after allergen was given (r = 0.54, p = 0.044 and r = 0.82, p less than 0.001, respectively). The findings demonstrate eosinophil kinetics are related to the occurrence of late-phase reactions and to the associated worsening of bronchial hyperreactivity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
458-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2913891-Adult,
pubmed-meshheading:2913891-Allergens,
pubmed-meshheading:2913891-Asthma,
pubmed-meshheading:2913891-Bronchial Provocation Tests,
pubmed-meshheading:2913891-Circadian Rhythm,
pubmed-meshheading:2913891-Eosinophils,
pubmed-meshheading:2913891-Female,
pubmed-meshheading:2913891-Forced Expiratory Volume,
pubmed-meshheading:2913891-Histamine,
pubmed-meshheading:2913891-Humans,
pubmed-meshheading:2913891-Leukocyte Count,
pubmed-meshheading:2913891-Male,
pubmed-meshheading:2913891-Skin Tests,
pubmed-meshheading:2913891-Time Factors
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pubmed:year |
1989
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pubmed:articleTitle |
Falls in peripheral eosinophil counts parallel the late asthmatic response.
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pubmed:affiliation |
Osler Chest Unit, Churchill Hospital, Headington, Oxford, United Kingdom.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|