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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-3-3
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pubmed:abstractText |
The cytotoxic activities of culture supernates, crude cell extracts and cell-wall materials of Bacteroides gingivalis were investigated in vitro. Each component was cytotoxic to Vero cells and, to a lesser extent, Wi 38 cells. The cytotoxic agents had similar effects on the cell lines to butyric acid, propionic acid and a partially-purified trypsin-like protein extracted from a clinical isolate of B. gingivalis; the effects were eliminated by heat. Cytotoxic materials obtained from young cultures were more susceptible to heat than those from older cultures. The heart-labile substance inside and outside the bacterial cell in young cultures of B. gingivalis may contribute to its overall cytotoxic activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-2615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2913316-Animals,
pubmed-meshheading:2913316-Bacterial Proteins,
pubmed-meshheading:2913316-Bacteroides,
pubmed-meshheading:2913316-Cell Line,
pubmed-meshheading:2913316-Cell Survival,
pubmed-meshheading:2913316-Cell Wall,
pubmed-meshheading:2913316-Cytotoxins,
pubmed-meshheading:2913316-Fatty Acids,
pubmed-meshheading:2913316-Fibroblasts,
pubmed-meshheading:2913316-Humans,
pubmed-meshheading:2913316-Spectrophotometry,
pubmed-meshheading:2913316-Vero Cells
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pubmed:year |
1989
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pubmed:articleTitle |
Cytotoxic activity of crude extracts of Bacteroides gingivalis.
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pubmed:affiliation |
Department of Medical Microbiology, College of Medicine, Lagos, Nigeria.
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pubmed:publicationType |
Journal Article
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