Linked Life Data

2912116

Source:http://linkedlifedata.com/resource/pubmed/id/2912116

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-2-13
pubmed:abstractText
A patient with a left sensorimotor trigeminal neuropathy was found to have edema of the corneal stroma induced by cold. Examination at room temperature demonstrated an anesthetic left cornea with minimal injection of the left eye and multiple punctate epithelial erosions. Corneal thickness, mean endothelial cell size, coefficient of variation of cell size, endothelial permeability to fluorescein, and aqueous humor flow rate, measured at room temperature were similar in the two eyes. After 47 minutes in a cold room at 4 C, the corneal thickness in the left eye increased from 0.55 to 0.65 mm, whereas that of the right eye remained at 0.55 mm. During the period of maximum swelling, the left cornea had clinical stromal edema with folds in Descemet's membrane but no epithelial edema. After return to room temperature there was a gradual return to normal corneal thickness over three hours. Fluorophotometry showed no evidence of increased endothelial permeability during corneal swelling in the left eye. Specular microscopy after 15 minutes of cold exposure demonstrated many swollen and irregular endothelial cells with darkened areas between cells in the left eye. Sensory nerve deficiency in the human cornea can produce an abnormal sensitivity to cold, resulting in defective control of corneal hydration. This study suggests that this effect may be on the endothelium.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0002-9394
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
107
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
52-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Edema of the corneal stroma induced by cold in trigeminal neuropathy.
pubmed:affiliation
Department of Ophthalmology, Mayo Foundation, Rochester, Minnesota 55905.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports, Research Support, Non-U.S. Gov't