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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1989-2-23
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pubmed:databankReference |
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pubmed:abstractText |
We have isolated the Xenopus homolog (Xint-1) of the mouse protooncogene int-1 from a neurula stage 17 cDNA library. The deduced protein sequence of Xint-1 includes 371 amino acids. The Xint-1 protein is more similar to the mammalian int-1 product (69%), than to the Drosophila counterpart of int-1, wingless (50%). Xint-1 shares several characteristics of secreted proteins with the other int-1 homologs: it has a hydrophobic leader, multiple conserved potential N-linked glycosylation sites and is rich in cysteine residues. All 23 cysteines are conserved in the three proteins. Xint-1 is transiently expressed during the neurula stages of early Xenopus development.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-16453776,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2429320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2440586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2441873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2443340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2453290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-271968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2828922,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2890437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2897242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2971536,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-2998762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3003692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3076290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3111720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3119404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-319365,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3282172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3313277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3323883,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3576203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3594565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3665770,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3714490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-3996185,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-46836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-518835,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6091914,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6167991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6297757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6312838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6326836,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6502707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6548550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2911462-6685077
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0305-1048
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-8
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
pubmed-meshheading:2911462-Amino Acid Sequence,
pubmed-meshheading:2911462-Animals,
pubmed-meshheading:2911462-Base Sequence,
pubmed-meshheading:2911462-DNA,
pubmed-meshheading:2911462-Drosophila,
pubmed-meshheading:2911462-Embryo, Nonmammalian,
pubmed-meshheading:2911462-Female,
pubmed-meshheading:2911462-Genes,
pubmed-meshheading:2911462-Mice,
pubmed-meshheading:2911462-Molecular Sequence Data,
pubmed-meshheading:2911462-Nervous System,
pubmed-meshheading:2911462-Proto-Oncogenes,
pubmed-meshheading:2911462-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2911462-Transcription, Genetic,
pubmed-meshheading:2911462-Xenopus laevis
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pubmed:year |
1989
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pubmed:articleTitle |
Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development.
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pubmed:affiliation |
Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht.
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pubmed:publicationType |
Journal Article,
Comparative Study
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