Linked Life Data

2911460

Source:http://linkedlifedata.com/resource/pubmed/id/2911460

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-2-22
pubmed:abstractText
A complicated interaction between outgoing and incoming protein transport occurs in eucaryotic cells. The incoming protein transport commences when protein molecules (ligands) cleave to specific glycoprotein- or glycolipid-receptors on the cell surfaces for endocytosis thereby. This can proceed in two types of membrane vesicle. Endocytosed ligands and receptors are transported from the surface of the cell to its endosomal system where a dissociation of the ligand from its receptor and sorting with regard to its next destination may occur. There are a good many possibilities of intracellular transport, depending on which ligand/receptor complex is at issue. Thus ligands and receptors can be transported back to the cell surface (recycling), across e.g. a polarized epithelial cell (transcytosis) to the lysosomes, and to the cell's Golgi apparatus. Apart from a large number of physiological ligands, viruses and diverse bacterial and plant toxins are also endocytosed. This allows scope for a therapeutic use of endocytosis.
pubmed:language
dan
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0029-1420
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Endocytosis, intracellular transport and sorting of proteins].
pubmed:publicationType
Journal Article, English Abstract