| pubmed-article:2911120 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C0042216 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C0035681 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C0596988 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C1283195 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C0205232 | lld:lifeskim |
| pubmed-article:2911120 | lifeskim:mentions | umls-concept:C1711351 | lld:lifeskim |
| pubmed-article:2911120 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:2911120 | pubmed:dateCreated | 1989-2-23 | lld:pubmed |
| pubmed-article:2911120 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2911120 | pubmed:abstractText | We have mapped the temperature-sensitive (ts) lesions of three mutants, ts51, ts53, and ts65, and two other mutants, ts7 and ts20, to regions on the vaccinia virus genome that encode the 147- and 22-kilodalton subunits of the viral DNA-dependent RNA polymerase, respectively. Plasmid and bacteriophage clones from the HindIII J region and the region spanning the HindIII J-H junction were used in marker rescue experiments to map the mutations. Sequence analysis of the region encoding the 22-kilodalton subunit in the wild-type, ts7, and ts20 viruses revealed a single base change in the mutants compared with that in the wild-type virus. The identification of these RNA polymerase mutants provides us with tools to understand transcription and its regulation in vaccinia virus. | lld:pubmed |
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| pubmed-article:2911120 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2911120 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2911120 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2911120 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2911120 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:2911120 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:2911120 | pubmed:author | pubmed-author:ConditR CRC | lld:pubmed |
| pubmed-article:2911120 | pubmed:author | pubmed-author:ThompsonC LCL | lld:pubmed |
| pubmed-article:2911120 | pubmed:author | pubmed-author:Hooda-Dhingra... | lld:pubmed |
| pubmed-article:2911120 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2911120 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:2911120 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2911120 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2911120 | pubmed:pagination | 705-13 | lld:pubmed |
| pubmed-article:2911120 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2911120 | pubmed:meshHeading | pubmed-meshheading:2911120-... | lld:pubmed |
| pubmed-article:2911120 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2911120 | pubmed:articleTitle | Fine structure mapping of five temperature-sensitive mutants in the 22- and 147-kilodalton subunits of vaccinia virus DNA-dependent RNA polymerase. | lld:pubmed |
| pubmed-article:2911120 | pubmed:affiliation | Department of Biochemistry, State University of New York, Buffalo 14214. | lld:pubmed |
| pubmed-article:2911120 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2911120 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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