| pubmed-article:2905408 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0038454 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0014653 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0034705 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0012155 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0005823 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0220871 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0021149 | lld:lifeskim |
| pubmed-article:2905408 | lifeskim:mentions | umls-concept:C0086595 | lld:lifeskim |
| pubmed-article:2905408 | pubmed:issue | 25 | lld:pubmed |
| pubmed-article:2905408 | pubmed:dateCreated | 1989-2-16 | lld:pubmed |
| pubmed-article:2905408 | pubmed:abstractText | Following the suckling period, stroke-prone spontaneously hypertensive rats (SHR-SP) were fed semi-purified diets supplemented either with safflower seed oil (rich in linoleic acid) or with perilla seed oil (rich in alpha-linolenic acid). The mean survival time of male SHR-SP fed the perilla diet was longer than that fed the safflower diet by 17% (p less than 0.001) while the difference was 15% in female SHR-SP (p less than 0.05). The mean survival times of female SHR-SP were more than 40% longer than those of male SHR-SP in both dietary groups. Post-mortem examinations of brains revealed apoplexy-related symptoms as the major cause of the death in both dietary groups. The systolic blood pressure was lower by ca. 10% (21 mmHg) in the perilla group than in both the safflower group and conventional diet group. The eicosapentaenoate (20:5 n-3)/arachidonate (20:4 n-6) ratio of platelet phospholipids in spontaneously hypertensive rat (SHR), a measure of platelet aggregability, was much higher in the perilla group than in the safflower group. Thus, increasing the dietary alpha-linolenate/linoleate ratio resulted in an increased mean survival time of SHR-SP rats, possibly by lowering blood pressure and platelet aggregability. | lld:pubmed |
| pubmed-article:2905408 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2905408 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2905408 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2905408 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:SaitoMM | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:NaitoYY | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:ShimokawaTT | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:HoriTT | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:OkuyamaHH | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:MatsubaraMM | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:MoriuchiAA | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:NagaeYY | lld:pubmed |
| pubmed-article:2905408 | pubmed:author | pubmed-author:KabasawaHH | lld:pubmed |
| pubmed-article:2905408 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2905408 | pubmed:volume | 43 | lld:pubmed |
| pubmed-article:2905408 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2905408 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2905408 | pubmed:pagination | 2067-75 | lld:pubmed |
| pubmed-article:2905408 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:2905408 | pubmed:meshHeading | pubmed-meshheading:2905408-... | lld:pubmed |
| pubmed-article:2905408 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:2905408 | pubmed:articleTitle | Effect of dietary alpha-linolenate/linoleate balance on mean survival time, incidence of stroke and blood pressure of spontaneously hypertensive rats. | lld:pubmed |
| pubmed-article:2905408 | pubmed:affiliation | Faculty of Pharmaceutical Sciences, Nagoya City University, Japan. | lld:pubmed |
| pubmed-article:2905408 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2905408 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
