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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1989-2-17
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pubmed:abstractText |
Sixty children undergoing surgery were allocated, according to weight, to three equal groups. Each child received a loading dose of vecuronium 80 micrograms kg-1 followed immediately by an infusion set initially at 1.4 micrograms kg-1 min-1. The subsequent intense neuromuscular blockade was assessed using the post-tetanic count (PTC). Maintaining the PTC between 5 and 15 ensured adequate paralysis which was antagonized easily 6-18 min after stopping the infusion. However, the duration of the initial intense block was unpredictable and the use of a peripheral nerve stimulator is advisable, particularly in smaller infants (less than 5 kg). The results suggest that vecuronium accumulated after 3 h infusion and that has less presynaptic effect than atracurium.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0007-0912
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
551-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2905144-Adolescent,
pubmed-meshheading:2905144-Child,
pubmed-meshheading:2905144-Child, Preschool,
pubmed-meshheading:2905144-Electric Stimulation,
pubmed-meshheading:2905144-Humans,
pubmed-meshheading:2905144-Infant,
pubmed-meshheading:2905144-Infant, Newborn,
pubmed-meshheading:2905144-Infusions, Intravenous,
pubmed-meshheading:2905144-Muscle Contraction,
pubmed-meshheading:2905144-Neuromuscular Junction,
pubmed-meshheading:2905144-Time Factors,
pubmed-meshheading:2905144-Vecuronium Bromide
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pubmed:year |
1988
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pubmed:articleTitle |
Post-tetanic count and intense neuromuscular blockade with vecuronium in children.
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pubmed:affiliation |
Hospital For Sick Children, London.
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pubmed:publicationType |
Journal Article
|