Linked Life Data

2904329

Source:http://linkedlifedata.com/resource/pubmed/id/2904329

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-1-26
pubmed:abstractText
1. The effect of hibernation on cerebral cortical concentrations of cholecystokinin and vasoactive intestinal peptide was investigated in the golden mantled ground squirrel (Citellus lateralis). 2. During hibernation, cortical brain weight decreased to 83% of the non-hibernating weight. 3. The concentration of the small form of CCK was significantly reduced. The concentration of the large forms of immunoreactive CCK did not significantly change during hibernation. The molecular forms of CCK appeared the same both before and during hibernation. 4. Of note, the concentration of vasoactive intestinal peptide significantly increased during hibernation. 5. Since there was a three-fold reduction in the ratio of large to small forms of CCK during hibernation, this suggests that post-translational processing of the precursor peptides are markedly reduced during hibernation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9629
pubmed:author
pubmed:issnType
Print
pubmed:volume
91
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-81
pubmed:dateRevised
2008-10-30
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Cholecystokinin (CCK) and vasoactive intestinal peptide (VIP) in the cerebral cortex of the non-hibernating and hibernating golden mantled ground squirrel.
pubmed:affiliation
Veterans Administration Medical Center, Bronx, NY 10468.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.