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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1988-8-19
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pubmed:abstractText |
Twelve female guinea pigs were given estradiol and another 12 testosterone for 18 days. A third group of 15 animals underwent oophorectomy and a group of 8 animals served as controls. Gastric and pancreatic D-cells were quantitated in all four groups. Oophorectomy and androgens significantly increased and estrogens significantly decreased gastric D-cell populations. Additionally, estrogens significantly decreased D-cell population in pancreatic islets. It is concluded that the alterations in gastric and pancreatic D-cell populations, which are induced by sex hormone administration and oophorectomy, possibly reflect a hormonal adaptive attempt to restore gastric secretory functions within the normal range.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0014-312X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
144-8
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pubmed:dateRevised |
2006-11-30
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pubmed:meshHeading |
pubmed-meshheading:2899029-Animals,
pubmed-meshheading:2899029-Estradiol,
pubmed-meshheading:2899029-Female,
pubmed-meshheading:2899029-Gastric Mucosa,
pubmed-meshheading:2899029-Gonadal Steroid Hormones,
pubmed-meshheading:2899029-Guinea Pigs,
pubmed-meshheading:2899029-Immunohistochemistry,
pubmed-meshheading:2899029-Islets of Langerhans,
pubmed-meshheading:2899029-Ovariectomy,
pubmed-meshheading:2899029-Ovary,
pubmed-meshheading:2899029-Somatostatin,
pubmed-meshheading:2899029-Testosterone
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pubmed:year |
1988
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pubmed:articleTitle |
Fundic, antral and pancreatic D-cell population changes following oophorectomy and sex hormone administration in guinea pigs. Experimental immunocytochemical study.
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pubmed:affiliation |
Second Surgical Department, Athens Naval and Veterans Hospital, Greece.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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