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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1988-8-11
|
| pubmed:abstractText |
Mutants of Vibrio cholerae defective in intestinal colonization have been constructed. Characterization of these mutants has led to the identification of a gene cluster involved in the assembly of a pilus colonization factor called TCP. The tcp operon has been cloned and strains of V. cholerae have been constructed that overproduce this pilus and the B subunit of cholera toxin. Together these studies may contribute to the eventual construction of efficient live and killed, oral cholera vaccines.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0264-410X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
151-4
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2898843-Administration, Oral,
pubmed-meshheading:2898843-Cholera Vaccines,
pubmed-meshheading:2898843-Cloning, Molecular,
pubmed-meshheading:2898843-DNA Transposable Elements,
pubmed-meshheading:2898843-Fimbriae, Bacterial,
pubmed-meshheading:2898843-Gene Expression Regulation,
pubmed-meshheading:2898843-Mutation,
pubmed-meshheading:2898843-Vaccines, Attenuated,
pubmed-meshheading:2898843-Vibrio cholerae
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Safe, live Vibrio cholerae vaccines?
|
| pubmed:affiliation |
Department of Microbiology and Immunology, University of Tennessee, Memphis 38163.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
|