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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
27
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pubmed:dateCreated |
1979-11-29
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pubmed:abstractText |
The concentrations of the primary prostaglandins (PG) F-2alpha and E-2 and the metabolite 13,14-dihydro-15-oxo-prostaglandin (PGFM) in maternal and fetal plasma and in allantoic fluid were measured in chronically catheterized mares and fetuses. A gradual rise in all 3 PGs occurred with increasing gestational age. PGE-2 and PGF-2 alpha levels were highest in the allantoic fluid and lowest in the maternal plasma, whereas PGFM concentrations were greatest in maternal plasma. Significant venous-arterial plasma differences in PGFM concentration were detected across the uterine circulation between 180 and 280 days gestation. The 3--5-fold rise in maternal PGFM associated with fasting or intrauterine surgery was virtually abolished by meclofenamic acid, a prostaglandin synthetase inhibitor. Increases in PGE-2 and PGF-2 alpha in the fetal fluids preceded premature delivery of the foal, while PG changes in maternal plasma were minimal even 10--20 h before delivery.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0449-3087
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
531-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:289833-Allantois,
pubmed-meshheading:289833-Animals,
pubmed-meshheading:289833-Extracellular Space,
pubmed-meshheading:289833-Female,
pubmed-meshheading:289833-Fetal Blood,
pubmed-meshheading:289833-Food Deprivation,
pubmed-meshheading:289833-Gestational Age,
pubmed-meshheading:289833-Horses,
pubmed-meshheading:289833-Labor, Obstetric,
pubmed-meshheading:289833-Pregnancy,
pubmed-meshheading:289833-Pregnancy, Animal,
pubmed-meshheading:289833-Prostaglandins,
pubmed-meshheading:289833-Prostaglandins E,
pubmed-meshheading:289833-Prostaglandins F
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pubmed:year |
1979
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pubmed:articleTitle |
Prostaglandins in maternal and fetal plasma and in allantoic fluid during the second half of gestation in the mare.
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pubmed:publicationType |
Journal Article
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