rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
8597
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pubmed:dateCreated |
1988-7-11
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pubmed:abstractText |
In a study of treatment by zidovudine in 106 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex, an acute meningo-encephalitic illness developed in 4 of 21 patients within 17 days after the dose of zidovudine had had to be reduced because of myelotoxicity. 3 of the 4 patients had previous clinical evidence of HIV encephalopathy. AIDS-related opportunist infection of the central nervous system was excluded. This acute meningo-encephalitic illness probably results from an increase in HIV replication following dose reduction.
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pubmed:grant |
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0140-6736
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
4
|
pubmed:volume |
1
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1249-52
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:2897518-AIDS-Related Complex,
pubmed-meshheading:2897518-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2897518-Acute Disease,
pubmed-meshheading:2897518-Adult,
pubmed-meshheading:2897518-Antiviral Agents,
pubmed-meshheading:2897518-Follow-Up Studies,
pubmed-meshheading:2897518-HIV,
pubmed-meshheading:2897518-Homosexuality,
pubmed-meshheading:2897518-Humans,
pubmed-meshheading:2897518-Male,
pubmed-meshheading:2897518-Meningoencephalitis,
pubmed-meshheading:2897518-Middle Aged,
pubmed-meshheading:2897518-Neutropenia,
pubmed-meshheading:2897518-Thrombocytopenia,
pubmed-meshheading:2897518-Thymidine,
pubmed-meshheading:2897518-Virus Replication,
pubmed-meshheading:2897518-Zidovudine
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pubmed:year |
1988
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pubmed:articleTitle |
Acute meningo-encephalitis on dose reduction of zidovudine.
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pubmed:affiliation |
Department of Immunology, St Mary's Hospital, London.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|