Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1988-6-9
pubmed:abstractText
The place and time of synthesis of the circumsporozoite protein of P. falciparum was analysed with a monoclonal antibody directed against the (NANP)3 repetitive epitope of the CS protein. By using an indirect fluorescent antibody test the epitope could be detected on the oocyst 7 days after infection and 3 days before the appearance of mature sporozoites. Using the Western blot technique, 3 polypeptides from midgut preparations were recognized by the (NANP)3-specific monoclonal antibody from the day 9 of infection onwards. The circumsporozoite precipitation reaction could be induced in sporozoites from either the midgut or the salivary glands 11 days after a blood meal. A similar reactivity of midgut-sporozoites and salivary gland-sporozoites was observed with antisporozoite antisera. Not all sporozoites recovered from the midgut showed a precipitation reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-706X
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-65
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Formation of the circumsporozoite protein of Plasmodium falciparum in Anopheles stephensi.
pubmed:affiliation
Swiss Tropical Institute, Basel, Switzerland.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't