Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1988-6-9
|
pubmed:abstractText |
Infections of T. brucei in the rabbit were found to relapse after chemotherapy. The results indicated that 25 mg/kg diminazene aceturate given 3 days after infection resulted in a complete cure but if given 7 days after infection relapses frequently occurred. However, treatment was apparently successful if delayed until 14 or 21 days. Six of the rabbits originally treated with diminazene aceturate on day 7 were treated with suramin 21 days later; in 3 rabbits the infections relapsed. In all rabbits in which drug treatment was not curative, the clinical condition nevertheless improved. An attempt to locate a cryptic focus of infection in rabbits was unsuccessful.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0001-706X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
45
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
45-54
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2896445-Amidines,
pubmed-meshheading:2896445-Animals,
pubmed-meshheading:2896445-Diminazene,
pubmed-meshheading:2896445-Female,
pubmed-meshheading:2896445-Male,
pubmed-meshheading:2896445-Mice,
pubmed-meshheading:2896445-Rabbits,
pubmed-meshheading:2896445-Recurrence,
pubmed-meshheading:2896445-Suramin,
pubmed-meshheading:2896445-Trypanosoma brucei brucei,
pubmed-meshheading:2896445-Trypanosomiasis, African
|
pubmed:year |
1988
|
pubmed:articleTitle |
The relapse of Trypanosoma brucei brucei infections after chemotherapy in rabbits.
|
pubmed:affiliation |
Kenya Trypanosomiasis Research Institute (KETRI), Muguga, Kikuyu.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|