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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1988-4-11
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pubmed:abstractText |
Three of 6 patients with spastic paraparesis in Lima, Peru, were found to have antibodies to human T-lymphotropic virus type I (HTLV-I). Blood and cerebrospinal fluid antibodies were confirmed by Western blot analysis. Multilobulated lymphocytes in blood and cerebrospinal fluid of the index case stained with monoclonal antibodies for T-helper cells and for T10, an activation marker. Blood mononuclear cells from patients with HTLV-I-associated myelopathy showed spontaneous proliferation in culture, evidence of interleukin-2 receptors, and decreased natural killer cell activity.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0364-5134
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23 Suppl
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S151-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2894807-Adult,
pubmed-meshheading:2894807-Aged,
pubmed-meshheading:2894807-Antibodies, Viral,
pubmed-meshheading:2894807-Blood Cells,
pubmed-meshheading:2894807-Cell Division,
pubmed-meshheading:2894807-Deltaretrovirus Antibodies,
pubmed-meshheading:2894807-Deltaretrovirus Infections,
pubmed-meshheading:2894807-Female,
pubmed-meshheading:2894807-Humans,
pubmed-meshheading:2894807-Leukocytes, Mononuclear,
pubmed-meshheading:2894807-Male,
pubmed-meshheading:2894807-Middle Aged,
pubmed-meshheading:2894807-Muscle Spasticity,
pubmed-meshheading:2894807-Myelitis,
pubmed-meshheading:2894807-Paraplegia,
pubmed-meshheading:2894807-Peru,
pubmed-meshheading:2894807-T-Lymphocytes
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pubmed:year |
1988
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pubmed:articleTitle |
Spastic paraparesis and HTLV-I infection in Peru.
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pubmed:affiliation |
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
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