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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1988-2-23
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pubmed:abstractText |
Providencia stuartii was the most prevalent bacterial species isolated, for one year, from weekly urine specimens from 51 long-term catheterized patients. Significantly more strains causing bacteriuric episodes of long duration expressed MR/K (mannose-resistant/Klebsiella-like) hemagglutination (74%) than did those causing episodes of short duration (26%; P = .004). Isolates expressing MR/K hemagglutinin bound in higher numbers to catheter material (P = .023) than did those not expressing this hemagglutinin. Significantly more strains causing bacteriuric episodes of short duration expressed the mannose-sensitive (MS) hemagglutinin (43%) than did those causing episodes of long duration (7%; P = .014). Isolates expressing MS hemagglutinin bound significantly more 125I-labeled Tamm-Horsfall protein (THP) than did isolates not expressing this hemagglutinin (P = .0001). Our results indicate that MR/K hemagglutinin plays an important role in the ability of P. stuartii to persist and suggest that MR/K adheres to the catheter. Conversely, MS hemagglutinin binds to THP and may prevent persistence of P. stuartii in the catheterized urinary tract.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Hemagglutinins,
http://linkedlifedata.com/resource/pubmed/chemical/Mannose,
http://linkedlifedata.com/resource/pubmed/chemical/Mucoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/UMOD protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Uromodulin
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
157
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
264-71
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2891774-Aged,
pubmed-meshheading:2891774-Aged, 80 and over,
pubmed-meshheading:2891774-Bacterial Adhesion,
pubmed-meshheading:2891774-Bacteriuria,
pubmed-meshheading:2891774-Catheters, Indwelling,
pubmed-meshheading:2891774-Female,
pubmed-meshheading:2891774-Fimbriae, Bacterial,
pubmed-meshheading:2891774-Hemagglutination,
pubmed-meshheading:2891774-Hemagglutinins,
pubmed-meshheading:2891774-Humans,
pubmed-meshheading:2891774-Male,
pubmed-meshheading:2891774-Mannose,
pubmed-meshheading:2891774-Mucoproteins,
pubmed-meshheading:2891774-Proteus,
pubmed-meshheading:2891774-Proteus Infections,
pubmed-meshheading:2891774-Providencia,
pubmed-meshheading:2891774-Urinary Catheterization,
pubmed-meshheading:2891774-Uromodulin
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pubmed:year |
1988
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pubmed:articleTitle |
MR/K hemagglutination of Providencia stuartii correlates with adherence to catheters and with persistence in catheter-associated bacteriuria.
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pubmed:affiliation |
Department of Medicine, University of Maryland School of Medicine, Baltimore 21201.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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