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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1987-11-18
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pubmed:abstractText |
Since metronidazole (M) was found to be effective in Crohn's disease, we evaluated its efficacy in the treatment of active ulcerative colitis (UC). Forty-six outpatients with acute, nonsevere UC were studied. Forty-two concluded the trial. Twenty-three received M 1.35 g/day and 19 received sulfasalazine (S) 4.5 g/day for 28 days in a randomized double-blind study. Six of 23 receiving M improved (26%) as against 13 of 19 patients receiving S (68%) (p less than 0.01). No significant side effects were noted. We conclude that M is ineffective in the therapy of an acute attack of UC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0192-0790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
415-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2888801-Acute Disease,
pubmed-meshheading:2888801-Clinical Trials as Topic,
pubmed-meshheading:2888801-Colitis, Ulcerative,
pubmed-meshheading:2888801-Double-Blind Method,
pubmed-meshheading:2888801-Female,
pubmed-meshheading:2888801-Humans,
pubmed-meshheading:2888801-Israel,
pubmed-meshheading:2888801-Male,
pubmed-meshheading:2888801-Metronidazole,
pubmed-meshheading:2888801-Random Allocation,
pubmed-meshheading:2888801-Sulfasalazine
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pubmed:year |
1987
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pubmed:articleTitle |
A comparative study of metronidazole and sulfasalazine in active, not severe, ulcerative colitis. An Israeli multicenter trial.
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pubmed:affiliation |
Department of Gastroenterology, Ichilov Hospital, Tel Aviv, Israel.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|