rdf:type |
|
lifeskim:mentions |
umls-concept:C0001613,
umls-concept:C0004788,
umls-concept:C0007776,
umls-concept:C0022655,
umls-concept:C0027882,
umls-concept:C0034693,
umls-concept:C0205101,
umls-concept:C0205322,
umls-concept:C0237753,
umls-concept:C0599668,
umls-concept:C1280500,
umls-concept:C1517945,
umls-concept:C1708517,
umls-concept:C1883709
|
pubmed:issue |
2
|
pubmed:dateCreated |
1987-11-20
|
pubmed:abstractText |
Ibotenic acid injections into the nucleus basalis (Ch4) resulted in a near-total loss of cortical cholinesterase fibers. This loss of cholinergic input is irreversible for at least 6 months. The degeneration of cholinergic input has no transsynaptic effect upon the number of cortical somatostatinergic, cholinergic and cholinesterase-positive (cholinoceptive) neurons.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0006-8993
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
11
|
pubmed:volume |
417
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
385-8
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:2888515-Acetylcholinesterase,
pubmed-meshheading:2888515-Animals,
pubmed-meshheading:2888515-Basal Ganglia,
pubmed-meshheading:2888515-Cell Count,
pubmed-meshheading:2888515-Cerebral Cortex,
pubmed-meshheading:2888515-Choline O-Acetyltransferase,
pubmed-meshheading:2888515-Cholinergic Fibers,
pubmed-meshheading:2888515-Ibotenic Acid,
pubmed-meshheading:2888515-Immunoenzyme Techniques,
pubmed-meshheading:2888515-Male,
pubmed-meshheading:2888515-Neurons,
pubmed-meshheading:2888515-Oxazoles,
pubmed-meshheading:2888515-Rats,
pubmed-meshheading:2888515-Rats, Inbred Strains,
pubmed-meshheading:2888515-Somatostatin
|
pubmed:year |
1987
|
pubmed:articleTitle |
Cortical effects of neurotoxic damage to the nucleus basalis in rats: persistent loss of extrinsic cholinergic input and lack of transsynaptic effect upon the number of somatostatin-containing, cholinesterase-positive, and cholinergic cortical neurons.
|
pubmed:affiliation |
Charles A. Dana Research Institute of Beth Israel Hospital, Boston, MA 02215.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|