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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1987-9-14
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pubmed:abstractText |
Auranofin in the mucosal fluid inhibited the active Na+-dependent absorption of taurocholic acid by everted sacs of rat ileum. It did not however, affect the passive uptake of taurocholic acid by sacs of mid-intestine. The inhibition by auranofin of active bile acid absorption could result from its previously demonstrated ability to inhibit Na+, K+-ATPase activity. A reduction in the reabsorption of bile acids by the ileum may contribute to the diarrhoea experienced by some patients taking auranofin.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0022-3573
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
572-3
|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2886633-Animals,
pubmed-meshheading:2886633-Auranofin,
pubmed-meshheading:2886633-Bile Acids and Salts,
pubmed-meshheading:2886633-Body Water,
pubmed-meshheading:2886633-Diarrhea,
pubmed-meshheading:2886633-Ileum,
pubmed-meshheading:2886633-Male,
pubmed-meshheading:2886633-Permeability,
pubmed-meshheading:2886633-Rats,
pubmed-meshheading:2886633-Sodium-Potassium-Exchanging ATPase
|
pubmed:year |
1987
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pubmed:articleTitle |
Auranofin inhibits the active uptake of bile acid by rat ileum.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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