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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1987-9-17
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pubmed:abstractText |
Enzymes of heme synthesis, porphyrins and heme content of regenerating rat livers were examined. During the first three days of regeneration the weights of livers of one-third and two-third hepatectomized rats increased 1.5-fold and 2.7-fold and the activity of porphobilinogen deaminase increased 2-fold and 4-fold and was inversely correlated with ferrochelatase activity. delta-Aminolevulinic acid synthase and delta-aminolevulinic acid dehydratase activities were reduced. Concomitantly an increase in the concentration of porphyrins and a decrease in that of heme were observed. The changes in the biosynthetic pathway of heme during rapid growth of the liver are discussed.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0014-2956
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
663-6
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pubmed:dateRevised |
2007-7-23
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pubmed:meshHeading |
pubmed-meshheading:2886336-Ammonia-Lyases,
pubmed-meshheading:2886336-Animals,
pubmed-meshheading:2886336-Ferrochelatase,
pubmed-meshheading:2886336-Heme,
pubmed-meshheading:2886336-Hydroxymethylbilane Synthase,
pubmed-meshheading:2886336-Liver,
pubmed-meshheading:2886336-Liver Regeneration,
pubmed-meshheading:2886336-Male,
pubmed-meshheading:2886336-Organ Size,
pubmed-meshheading:2886336-Porphyrins,
pubmed-meshheading:2886336-Rats,
pubmed-meshheading:2886336-Rats, Inbred Strains,
pubmed-meshheading:2886336-Tyrosine Transaminase
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pubmed:year |
1987
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pubmed:articleTitle |
The heme biosynthetic pathway in the regenerating rat liver. The relation between enzymes of heme synthesis and growth.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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