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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8548
|
pubmed:dateCreated |
1987-7-31
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pubmed:abstractText |
10 patients with the acquired immunodeficiency syndrome whose respiratory failure due to Pneumocystis carinii pneumonia (PCP) was deteriorating rapidly had 7 days of intravenous methylprednisolone added to their antibiotic regimen. 8 similar patients were treated with antibiotic therapy alone. 9 of the 10 methylprednisolone-treated patients survived their episode of PCP, compared with 2 of the 8 conventionally treated patients. Clinical improvement was evident within 2 days of the start of steroid therapy, and in none of the 10 patients did clinical deterioration or recurrence of PCP occur on cessation of steroid therapy. In 1 steroid-treated patient disseminated herpes zoster developed 2 days after discontinuation of methylprednisolone. Methylprednisolone seems to be a useful adjunctive therapeutic agent for patients with AIDS in whom Pneumocystis carinii is the sole respiratory pathogen.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0140-6736
|
pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
27
|
pubmed:volume |
1
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1477-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2885462-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2885462-Acute Disease,
pubmed-meshheading:2885462-Adrenal Cortex Hormones,
pubmed-meshheading:2885462-Adult,
pubmed-meshheading:2885462-Clinical Trials as Topic,
pubmed-meshheading:2885462-Follow-Up Studies,
pubmed-meshheading:2885462-Homosexuality,
pubmed-meshheading:2885462-Humans,
pubmed-meshheading:2885462-Male,
pubmed-meshheading:2885462-Methylprednisolone,
pubmed-meshheading:2885462-Pneumonia, Pneumocystis
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pubmed:year |
1987
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pubmed:articleTitle |
Corticosteroids as adjunctive therapy in treatment of Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|