Linked Life Data

2880391

Source:http://linkedlifedata.com/resource/pubmed/id/2880391

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-3-2
pubmed:abstractText
We studied cell surface markers in 8 men with T-cell chronic lymphocytic leukaemia, using fluorescein-conjugated monoclonal antibodies and a cell analyser/sorter. 1 patient's cells had a T-suppressor/cytolytic phenotype (T4-, T8+) and in 3 patients the phenotype was a T-helper cell (T4+, T8-) as described in retrovirus-associated adult T-cell lymphoma-leukaemia. In 4 patients, the cell phenotype was anomalous, with both helper and suppressor antigenic markers (T4+, T8+). Terminal deoxynucleotidyl transferase was positive in 1 of the 4 cases with dual markers. Clinical features and cytological characteristics, including cell size and the density of T8 antigen on the cell surface, showed no obvious correlation with the immunophenotypes, but study of additional cases is needed to evaluate this further.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0036-553X
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
421-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
T-cell chronic lymphocytic leukaemias and T-cell lymphoma-leukaemia: heterogeneity and anomalous cell markers.
pubmed:publicationType
Journal Article