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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-3-3
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pubmed:abstractText |
High affinity uptake of [14C]glutamate into rat striatal synaptosomes was reduced by 33% after bilateral cortical ablation. The lesion had no effect on striatal [14C]GABA uptake, but reduced 2-oxo-[14C]glutarate uptake by 67%. The results demonstrate the existence of a high-affinity uptake site for 2-oxoglutarate on glutamatergic nerve terminals and support the contention that this Krebs cycle intermediate may be used to replenish the neuronal pool of neurotransmitter glutamate. 2-Oxo-[14C]glutarate uptake may serve as a selective marker for glutamatergic neurones.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
227-31
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2880322-Animals,
pubmed-meshheading:2880322-Cerebral Cortex,
pubmed-meshheading:2880322-Corpus Striatum,
pubmed-meshheading:2880322-Glutamates,
pubmed-meshheading:2880322-Glutamic Acid,
pubmed-meshheading:2880322-Ketoglutaric Acids,
pubmed-meshheading:2880322-Male,
pubmed-meshheading:2880322-Neural Pathways,
pubmed-meshheading:2880322-Rats,
pubmed-meshheading:2880322-Rats, Inbred Strains,
pubmed-meshheading:2880322-Synaptosomes
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pubmed:year |
1986
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pubmed:articleTitle |
2-Oxo-[14C]glutarate is taken up by glutamatergic nerve terminals in the rat striatum.
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pubmed:publicationType |
Journal Article
|