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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1987-2-17
|
| pubmed:abstractText |
The effects on renal function of a single dose of six different beta-blockers (atenolol, propranolol, metoprolol, acebutolol, nadolol, and pindolol) have been evaluated in 51 hypertensive patients with normal glomerular filtration rate (GFR). Most drugs, except pindolol, induce a 10-20% decrease in GFR and renal plasma flow, although differences in the magnitude and the pattern of this fall are evident. The fractional excretion of sodium is generally depressed by 20-40%. These data suggest a limited renal tolerance of most beta-blockers during acute administration, irrespective of their pharmacological characteristics.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0250-8095
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6 Suppl 2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
15-9
|
| pubmed:dateRevised |
2007-2-14
|
| pubmed:meshHeading |
pubmed-meshheading:2879466-Adrenergic beta-Antagonists,
pubmed-meshheading:2879466-Glomerular Filtration Rate,
pubmed-meshheading:2879466-Humans,
pubmed-meshheading:2879466-Inulin,
pubmed-meshheading:2879466-Kidney,
pubmed-meshheading:2879466-Renal Circulation,
pubmed-meshheading:2879466-Sodium,
pubmed-meshheading:2879466-p-Aminohippuric Acid
|
| pubmed:year |
1986
|
| pubmed:articleTitle |
Acute renal effects of beta-blockers.
|
| pubmed:publicationType |
Journal Article
|