Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6C
pubmed:dateCreated
1987-1-30
pubmed:abstractText
The widespread prevalence of hypertension in the United States and the enormous expense and effort associated with its treatment necessitate a cost-conscious approach to evaluation and therapy. In the past, we have devoted too many resources to testing for rare diseases suspected of causing hypertension when it has been demonstrated that secondary causes are rare. Devoting resources to the effective treatment of essential hypertension itself should be a priority, because such treatment has been shown to reduce morbidity and mortality associated with hypertension and related cardiovascular diseases. Clinical and epidemiologic studies have demonstrated that treatment for hypertension should not be initiated unless diastolic blood pressure readings are 90 mm Hg or greater on three successive office visits. Treatment should be carried out in a step-wise fashion, using a non-pharmacologic approach only in situations in which hypertension is mild, target organ disease is absent, and compliance is favorable. Diuretics should be used as step-one drug therapy in most situations, because they are effective in the majority of patients, convenient to use, easy to titrate, and comparatively inexpensive. They do not cause salt and water retention, and side effects are usually minimal. When the use of diuretics is contraindicated, beta blockers are suitable alternatives, equally effective in most respects. When beta blockers or other non-diuretic drugs are used as step-one therapy and an additional drug is needed, diuretics can be used advantageously in conjunction with the step-one drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0002-9343
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
81
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Essential hypertension: cost-effective evaluation and treatment.
pubmed:publicationType
Journal Article, Review