Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1987-1-8
pubmed:abstractText
The effect of enkephalins, morphine and some neurotransmitters on spontaneous and evoked activity of neurons of the medial vestibular nucleus was investigated. The evoked activity was produced by an adequate stimulation of the vestibular apparatus. It was shown that neurons of this nucleus were highly sensitive to enkephalins, morphine, acetyl choline, GABA and L-glutamate (approximately 80% of the nerve cells were inhibited or excited in response to the micro-iontophoretic application of these substances). It was found that activation and depression effects of opioid peptides and morphine occurred due to the stimulation of mu- and delta-opiate receptors. It can be concluded that enkephalins modulate cholinergic and glutamatergic synaptic transfer in the medial vestibular nucleus. Together with opiate receptors, they participate in the perception and processing of vestibular information at the level of neurons of this nucleus.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0321-5040
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Chemical sensitivity of the neurons of the medial vestibular nucleus to enkephalins, acetylcholine, GABA and L-glutamate].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract