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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1987-1-20
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pubmed:abstractText |
In nine family pedigrees in which X-linked agammaglobulinemia (XLA) is segregating, a multi-point linkage analysis has been carried out. In each family, the map distance, d, between XLA and a fixed point in a known map of nine RFLP loci on the X chromosome was estimated by calculating the log likelihoods, L(d). Using a new method, the 10-point likelihood was approximated by appropriately combining three 4-point likelihoods. Homogeneity tests (admixture tests) were performed showing clear evidence for heterogeneity of XLA.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0340-6717
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
74
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
280-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2877937-Agammaglobulinemia,
pubmed-meshheading:2877937-Chromosome Mapping,
pubmed-meshheading:2877937-Genetic Markers,
pubmed-meshheading:2877937-Humans,
pubmed-meshheading:2877937-Lod Score,
pubmed-meshheading:2877937-Pedigree,
pubmed-meshheading:2877937-Polymorphism, Genetic,
pubmed-meshheading:2877937-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:2877937-X Chromosome
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pubmed:year |
1986
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pubmed:articleTitle |
Heterogeneity in the map distance between X-linked agammaglobulinemia and a map of nine RFLP loci.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|