Linked Life Data

2877876

Source:http://linkedlifedata.com/resource/pubmed/id/2877876

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-12-30
pubmed:abstractText
Vecuronium was administered as an intravenous bolus (50 micrograms kg-1) to 10 normal and 10 anephric patients. The elimination half-life was 50.7 +/- 20.3 min in normal patients and 67.826.3 min in anephric patients. The plasma clearance was 3.6 +/- 1.5 ml min-1 for normal patients and 4.5 +/- 2.6 ml min-1 kg-1 for anephric patients. Only the volume of the second compartment was statistically increased (+90%, P less than 0.05) in anephric patients. The duration of action in normal patients (25.3 +/- 9.8 min) was comparable to the duration of action in patients with renal failure (32.8 +/- 10.7 min), but the recovery index was prolonged (+45%, P less than 0.05) in anephric patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0265-0215
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
153-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Pharmacology of vecuronium in patients with end-stage renal failure.
pubmed:publicationType
Journal Article