rdf:type |
|
lifeskim:mentions |
umls-concept:C0010819,
umls-concept:C0011900,
umls-concept:C0022646,
umls-concept:C0035015,
umls-concept:C0205352,
umls-concept:C0450127,
umls-concept:C0677862,
umls-concept:C0936012,
umls-concept:C1510483,
umls-concept:C1548437,
umls-concept:C1882923
|
pubmed:issue |
8508
|
pubmed:dateCreated |
1986-10-30
|
pubmed:abstractText |
Fine-needle aspiration biopsy specimens of renal transplants were analysed by means of commercially available monoclonal antibodies and an immunoperoxidase stain. Three cellular features associated with acute cellular rejection were identified--heavy infiltrates of activated T cells or large mononuclear cells strongly expressing HLA-DR antigens, and HLA-DR expression by renal tubular cells. A combination of semiquantitative scores for these features correctly identified rejection in 32 of 34 cases, with no false positives in cases of cyclosporin nephrotoxicity or stable graft function.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0140-6736
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
20
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
645-50
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2876134-Antibodies, Monoclonal,
pubmed-meshheading:2876134-Azathioprine,
pubmed-meshheading:2876134-Biopsy, Needle,
pubmed-meshheading:2876134-Creatinine,
pubmed-meshheading:2876134-Cyclosporins,
pubmed-meshheading:2876134-Graft Rejection,
pubmed-meshheading:2876134-HLA-DR Antigens,
pubmed-meshheading:2876134-Histocytochemistry,
pubmed-meshheading:2876134-Humans,
pubmed-meshheading:2876134-Immunoenzyme Techniques,
pubmed-meshheading:2876134-Kidney Transplantation,
pubmed-meshheading:2876134-T-Lymphocytes
|
pubmed:year |
1986
|
pubmed:articleTitle |
Diagnosis of renal allograft rejection by analysis of fine-needle aspiration biopsy specimens with immunostains and simple cytology.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|