Linked Life Data

287518

Source:http://linkedlifedata.com/resource/pubmed/id/287518

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1979-9-25
pubmed:abstractText
A chemotactic factor inhibitor (CFI) was found in the serum of a patient with acute lymphoblastic leukemia. The factor was characterized as heat-labile, with activity against complement-dependent chemotactic factors and against the chemotactic factor produced by Escherichia coli. Normal sera and sera from other patients with acute leukemia also demonstrate heat-labile inhibitory activity against complement-dependent chemotactic factors but not against the E. coli-derived chemotactic factor. Supernatants from cultured lymphoblasts of the patient also possessed CFI activity similar in character to that found in his serum. It is suggested that in vivo the lymphoblasts were responsible for the chemotactic defect observed in his serum, presumably by manufacturing and releasing a chemotactic factor inactivator.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0006-4971
pubmed:author
pubmed:issnType
Print
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
412-20
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
A chemotactic inhibitor produced by blast cells and present in the serum of a patient with acute lymphoblastic leukemia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.