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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1986-7-2
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pubmed:abstractText |
Thirty-nine patients with second-stage essential hypertension were treated with Beta-adrenoblockers of different classes for 2.5 to 3 years. Two groups of patients were distinguished: 23 patients showing a regression of left-ventricular myocardial weight (group 1) and 16 patients without such developments (group 2). A significant decrease in arterial blood pressure (by 20-24%) and heart rate (by 15 to 18%) was recorded in both groups. Total peripheral resistance was changed insignificantly in group 1 and by 9.7% (p less than 0.05) in group 2. The end diastolic volume decreased by 5.4% (p less than 0.05) in group 1, and increased by 4.7% (p less than 0.05) in group 2. The end systolic volume decreased by 10.6% (p less than 0.05) in group 1 and increased by 5% (p greater than 0.1) in group 2. Myocardial contractility declined significantly in both groups (by 9.5% and 10.6%, respectively). Intramyocardial tension dropped by 13-20% (p less than 0.001) in both groups. Therefore, the regression of left-ventricular myocardial hypertrophy was shown to have a favorable effect on cardiac function.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Atenolol,
http://linkedlifedata.com/resource/pubmed/chemical/Nadolol,
http://linkedlifedata.com/resource/pubmed/chemical/Propanolamines,
http://linkedlifedata.com/resource/pubmed/chemical/Propranolol
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-9040
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
28-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2872357-Adrenergic beta-Antagonists,
pubmed-meshheading:2872357-Adult,
pubmed-meshheading:2872357-Antihypertensive Agents,
pubmed-meshheading:2872357-Atenolol,
pubmed-meshheading:2872357-Cardiomegaly,
pubmed-meshheading:2872357-Drug Therapy, Combination,
pubmed-meshheading:2872357-Female,
pubmed-meshheading:2872357-Humans,
pubmed-meshheading:2872357-Hypertension,
pubmed-meshheading:2872357-Male,
pubmed-meshheading:2872357-Middle Aged,
pubmed-meshheading:2872357-Nadolol,
pubmed-meshheading:2872357-Propanolamines,
pubmed-meshheading:2872357-Propranolol,
pubmed-meshheading:2872357-Time Factors
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pubmed:year |
1986
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pubmed:articleTitle |
[Regression of left-ventricular myocardial hypertrophy in patients with hypertension during long-term treatment with beta-adrenergic blockaders].
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pubmed:publicationType |
Journal Article,
English Abstract
|