Linked Life Data

2872055

Source:http://linkedlifedata.com/resource/pubmed/id/2872055

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-7-24
pubmed:abstractText
The effects of xamoterol on exercise capacity have been evaluated in 10 patients with angina pectoris and well-preserved left ventricular function. Compared to placebo a single 200 mg dose of xamoterol produced a slight but insignificant increase in exercise capacity. At maximum work load, ST-T segment depression was reduced (3 mm and 2.19 mm after placebo and xamoterol, respectively; p less than 0.05). The changes paralleled an insignificant reduction in maximal heart rate and pressure-rate product. At rest, xamoterol increased the heart rate from 80 to 86 beats/min. Thus, at rest, when sympathetic tone is low, xamoterol acts as a beta-receptor agonist but during exercise, when sympathetic tone is high, xamoterol acts as an antagonist and reduces myocardial ischaemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0031-6970
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
667-71
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Effects of xamoterol a new beta-adrenoceptor partial agonist, in patients with angina pectoris.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Controlled Clinical Trial