Linked Life Data

2871058

Source:http://linkedlifedata.com/resource/pubmed/id/2871058

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1986-6-9
pubmed:abstractText
A double-blind crossover comparison of clonidine and placebo was conducted in seven subjects afflicted with neuroleptic-induced tardive dyskinesia (TD). Subjects received either clonidine, 0.4 mg/day, or placebo for a period of 8 weeks and were then crossed over to the opposing treatment modality. The effects of clonidine on TD symptomatology could not be distinguished from those of placebo (p greater than 0.05). However, comparison of prestudy ratings of TD severity to poststudy ratings revealed a significant reduction in TD symptoms (p less than 0.01). Close analysis of the data indicates that clonidine's effect on TD may have carried over into the placebo phase of the study, masking any true differences between clonidine and placebo treatment. Other factors which may have contributed to the lack of significant findings are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0271-0749
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
88-92
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
The use of clonidine in the treatment of neuroleptic-induced tardive dyskinesia.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Controlled Clinical Trial