Linked Life Data

2866335

Source:http://linkedlifedata.com/resource/pubmed/id/2866335

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8467
pubmed:dateCreated
1986-1-2
pubmed:abstractText
Slime-producing and non-slime-producing strains of coagulase-negative staphylococci (CNS) were evaluated for nafcillin susceptibility in the presence and absence of polyvinylchloride (PVC) catheters. Semiquantitative roll cultures of catheters with adherent organisms after exposure to predicted bactericidal concentrations of nafcillin were carried out to assess survival of these organisms. Slime-producing and non-slime-producing CNS had similar minimum inhibitory (MIC) and bactericidal (MBC) concentrations in the absence of catheters and similar MIC in the presence of catheters. However, the mean MBC of slime-producing CNS, and to a lesser extent of non-slime-producing strains was higher in the presence than in the absence of catheters. Slime-producing CNS were recovered from PVC catheters after overnight incubation in cidal concentrations (greater than 4.0 micrograms/ml) of nafcillin (average 350 colony-forming units per 1 cm). Thus nafcillin-sensitive CNS strains, particularly those producing slime, are able to survive exposure to cidal concentrations of the drug when adherent to PVC catheters.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1266-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Influence of bacterial adherence to intravascular catheters on in-vitro antibiotic susceptibility.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.