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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1985-8-28
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pubmed:abstractText |
Four active metabolites that specifically inhibit acetyl CoA carboxylase, the late-limiting enzyme in fatty acid biosynthesis, have been isolated from a strain of Gongronella butleri mating type (+). Their chemical structures were determined to be octyl pentanedioic acid, 9-decenyl-1-pentenedioic acid, decanyl-1-pentenedioic acid, decanyl-2-pentenedioic acid, respectively. These compounds inhibited rat liver acetyl CoA carboxylase 50% at a concentration of 30 approximately 55 micrograms/ml.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-8820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
599-604
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2862131-Acetyl-CoA Carboxylase,
pubmed-meshheading:2862131-Animals,
pubmed-meshheading:2862131-Chemical Phenomena,
pubmed-meshheading:2862131-Chemistry,
pubmed-meshheading:2862131-Enzyme Inhibitors,
pubmed-meshheading:2862131-Fermentation,
pubmed-meshheading:2862131-Ligases,
pubmed-meshheading:2862131-Mucorales,
pubmed-meshheading:2862131-Rats
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pubmed:year |
1985
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pubmed:articleTitle |
Acetyl CoA carboxylase inhibitors from the fungus Gongronella butleri.
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pubmed:publicationType |
Journal Article
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