Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1985-7-12
pubmed:abstractText
Three groups of patients with medullary thyroid carcinoma treated for cure from an institution under standardized tumor stage were compared. For sporadic cases and all cases across groups, the observed survival rates at 10 years were significantly lower than expected based on persons from the West North Central region of the US of like age and sex born in the same calendar year. They were not different for patients with multiple endocrine neoplasia (MEN), type 2a and 2b. Mean ages were significantly different among the three groups: they were 48.5 years for sporadic, 37.7 for MEN 2a, and 23.4 for MEN 2b. Tumor-free survival rate after surgical treatment of MEN 2b was 36.6% at 5 years and 27.3% at 10 years, and was significantly lower in comparison with that of sporadic cases. Medullary carcinoma in patients with MEN 2b appeared to develop at an earlier mean age, with a higher frequency of nodal metastasis and a higher rate of tumor recurrence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2818-21
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Medullary carcinoma of thyroid. Biologic behavior of the sporadic and familial neoplasm.
pubmed:publicationType
Journal Article