Linked Life Data

2859614

Source:http://linkedlifedata.com/resource/pubmed/id/2859614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-6-20
pubmed:abstractText
Ovariectomized (OVX) and ovariectomized-adrenalectomized (OVX-ADX) rats were injected with estradiol benzoate (EB, 4.0 micrograms/rat) and received 44 hr by infusion into the ventromedial hypothalamic area one of the following treatments: norepinephrine (NE), clonidine (an alpha-agonist), isoproterenol (a beta-agonist) or a combination of clonidine and isoproterenol. Infusion of NE (200 ng/rat) induced lordosis in both OVX and OVX-ADX rats 15 minutes after its administration. NE-induced lordosis was blocked by systemic treatment with either the alpha-antagonist, prazosin (1.0 mg/kg), or the beta-antagonist, propranolol (4.0 mg/kg). Intrahypothalamic infusion of clonidine (200 ng/rat) or isoproterenol (200 ng/rat) induced lordosis behavior in OVX, but not in OVX-ADX rats, suggesting the involvement of adrenal secretions in this response. Combined administration of clonidine (100 ng/rat) and isoproterenol (100 ng/rat) induced lordosis behavior 15 minutes after its intrahypothalamic infusion in OVX-ADX animals. Results are discussed in relation to a model proposed for the induction of lordosis behavior involving steroid-NE interactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
613-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Potentiative action of alpha- and beta-adrenergic receptor stimulation in inducing lordosis behavior.
pubmed:publicationType
Journal Article