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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1985-5-21
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pubmed:abstractText |
We retrospectively reviewed the records of 12 patients from one institution (from 1970 through 1983) who had hyperinsulinism as a part of the multiple endocrine neoplasia, type 1 syndrome. All of the patients underwent surgical exploration: ten had subtotal pancreatectomies, one had enucleation, and one underwent a total pancreatectomy. There was no operative mortality. Preoperative and intraoperative localization studies (angiography and ultrasonography) tended to underestimate the number of pancreatic tumors. Ten patients had multiple B-cell adenomas (mean, 7.4), while two patients had single tumors. This study confirms that hyperinsulinism, when it occurs as part of the multiple endocrine neoplasia, type 1 syndrome, is usually due to multiple islet cell tumors, and that the islet cell tissue is probably diffusely dysplastic. Subtotal (85%) pancreatectomy is suggested as the procedure of choice for this subgroup of patients with hyperinsulinism.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0004-0010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
584-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2859009-Adenoma,
pubmed-meshheading:2859009-Adenoma, Islet Cell,
pubmed-meshheading:2859009-Adolescent,
pubmed-meshheading:2859009-Adult,
pubmed-meshheading:2859009-Carcinoma,
pubmed-meshheading:2859009-Child,
pubmed-meshheading:2859009-Female,
pubmed-meshheading:2859009-Humans,
pubmed-meshheading:2859009-Hyperinsulinism,
pubmed-meshheading:2859009-Male,
pubmed-meshheading:2859009-Middle Aged,
pubmed-meshheading:2859009-Multiple Endocrine Neoplasia,
pubmed-meshheading:2859009-Pancreatic Neoplasms,
pubmed-meshheading:2859009-Postoperative Complications,
pubmed-meshheading:2859009-Retrospective Studies
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pubmed:year |
1985
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pubmed:articleTitle |
Surgical management of hyperinsulinism in the multiple endocrine neoplasia, type 1 syndrome.
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pubmed:publicationType |
Journal Article
|