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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-11
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pubmed:abstractText |
Normal and lesioned rats exposed to 3 mg/kg i.p. endosulfan for 10 subsequent days showed elevated foot-shock fighting behaviour in septal and nigral brain-lesioned animals. Increased ipsilateral circling was noticed in unilateral-nigral lesioned rats. A marked decrease in locomotor activity and no seizure pattern were recorded in rats treated with chlorpromazine (CPz). Electroencephalographic recording on the tenth day of endosulfan exposure showed high-voltage slow activity (HVSA) with occasional spindles and 5-6 Hz amplitude of 200 microV. In the treated rats an increase in the concentration of dopamine (DA) and a decrease in serotonin (5-HT) were recorded in amygdaloid, septal and nigral brain-lesioned rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0378-4274
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-84
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:2858134-Aggression,
pubmed-meshheading:2858134-Agonistic Behavior,
pubmed-meshheading:2858134-Animals,
pubmed-meshheading:2858134-Chlorpromazine,
pubmed-meshheading:2858134-Dopamine,
pubmed-meshheading:2858134-Electroencephalography,
pubmed-meshheading:2858134-Endosulfan,
pubmed-meshheading:2858134-Female,
pubmed-meshheading:2858134-Humans,
pubmed-meshheading:2858134-Neurotransmitter Agents,
pubmed-meshheading:2858134-Rats,
pubmed-meshheading:2858134-Serotonin
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pubmed:year |
1985
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pubmed:articleTitle |
Role of neurotransmitters in endosulfan-induced aggressive behaviour in normal and lesioned rats.
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pubmed:publicationType |
Journal Article
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