Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-8-31
pubmed:abstractText
In order to characterize the pharmacological properties of post-junctional alpha-adrenoceptors, the vasoconstricting effects of the non-specific alpha-adrenoceptor agonist noradrenaline, of the specific alpha 1-adrenoceptor agonist phenylephrine and of the specific alpha 2-adrenoceptor agonist azepexole and the interaction with the calcium entry blockers nifedipine and diltiazem were studied in hand veins of eight healthy volunteers. Both subtypes of alpha-adrenoceptors could be demonstrated in human hand veins in vivo. The alpha 1-subtype seemed to prevail. Vasoconstriction induced by stimulation of either post-synaptic alpha 1- or alpha 2-adrenoceptors was reduced by the calcium entry blockers diltiazem and nifedipine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0952-1178
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S239-41
pubmed:dateRevised
2005-6-8
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Specific alpha-adrenoceptor-mediated vasoconstriction in human veins and interaction with the calcium entry blockers nifedipine and diltiazem.
pubmed:affiliation
Department of Internal Medicine, Klinikum Steglitz, Freie Universität Berlin, Federal Republic of Germany.
pubmed:publicationType
Journal Article