Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-8-31
pubmed:abstractText
The acute administration of anti-digoxin serum (ADS) caused a pronounced blood pressure decrease only in those hypertensive rats that were treated with desoxycorticosterone acetate (DOCA) and 1% saline from prepuberty. This was due to a rapid decrease in systemic resistance which was partially compensated by increased cardiac output. There were no similar effects of ADS in rats treated in the same manner in adulthood only. Different mechanisms might be responsible for blood pressure elevation induced by high salt intake in youth or in adulthood. The participation of endogenous digoxin-like factor in the maintenance of elevated systemic resistance in DOCA-salt hypertensive rats is a typical case.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0952-1178
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S17-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Endogenous digoxin-like factor contributes to the elevation of systemic resistance in rats exposed to high salt intake from prepuberty.
pubmed:affiliation
Institute of Physiology, Czechoslovak Academy of Sciences, Prague.
pubmed:publicationType
Journal Article