Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1990-4-11
|
| pubmed:abstractText |
From January 1975 to April 1987, 27 patients underwent surgical resection of non oat cell lung cancer and a single brain metastasis. There were 25 men and 2 women ranging in age from 37 to 70 years. In 21 cases the brain metastasis was synchronous while in 6 cases the onset was metachronous. In 17 cases, the site of the brain metastasis was supratentorial and in 10 cases it was located in the posterior fossa. The chest X-ray confirmed the primary lung tumour in 24 cases. In 3 cases, only bronchoscopy and cytology revealed the primary focus of the tumour. The lung cancer was located in the upper lobe in 25 patients. Upper lobectomy was performed in 23 patients, pneumonectomy in 3, and lower lobectomy in 1. There were no operative deaths. The cell type was adenocarcinoma in 19 cases, squamous cell carcinoma in 4 patients and large cell carcinoma in 4. Only the tumour and nodes were used for staging at thoracotomy. The classification was: 12 patients in stage I, 2 in stage II, and 13 in stage III. At conclusion of the study the longest survival was 68 months after thoracotomy. There was no significant difference in the duration of survival in patients over or under 50 years old. Better results were obtained in patients without node metastases at thoracotomy (median survival of 30 months and an overall 5-year survival of 35%), and in patients with supratentorial metastases (median survival of 22 months and an overall 5-year survival of 23.4%). Our experience confirms that combined surgery prolongs survival and improves the quality of life.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1010-7940
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
336-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2856106-Adult,
pubmed-meshheading:2856106-Aged,
pubmed-meshheading:2856106-Brain Neoplasms,
pubmed-meshheading:2856106-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:2856106-Female,
pubmed-meshheading:2856106-Humans,
pubmed-meshheading:2856106-Lung Neoplasms,
pubmed-meshheading:2856106-Lymphatic Metastasis,
pubmed-meshheading:2856106-Male,
pubmed-meshheading:2856106-Middle Aged,
pubmed-meshheading:2856106-Neoplasm Staging,
pubmed-meshheading:2856106-Quality of Life,
pubmed-meshheading:2856106-Recurrence,
pubmed-meshheading:2856106-Survival Rate
|
| pubmed:year |
1988
|
| pubmed:articleTitle |
Surgical therapy in lung cancer with single brain metastasis.
|
| pubmed:affiliation |
Thoracic Surgery Department A, De Gasperis, Milan, Italy.
|
| pubmed:publicationType |
Journal Article
|