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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1989-5-30
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pubmed:abstractText |
Adenohypophysis and hypothalamic bovine tissues were homogenized, lipid extracted, salt removed and loaded onto 2 successive mu Bondapak HPLC columns, semipreparative and analytic, respectively. In vitro sodium-pump inhibitory activity, recovered from each tissue, showed similar chromatographic patterns, but hypothalamus seems to contain a major hydrophobic material which appears at the end of the run, when acetonitrile gradient raised 40% approximately. Digitalis-like activity disappears along the purification procedure, and this fact suggests a clear dissociation between (Na/K)ATPase inhibition and digoxin-like activity, measured as crossing with digoxin antibodies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0730-0077
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
301-7
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pubmed:dateRevised |
2008-2-12
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pubmed:meshHeading |
pubmed-meshheading:2854013-Animals,
pubmed-meshheading:2854013-Cattle,
pubmed-meshheading:2854013-Chemical Fractionation,
pubmed-meshheading:2854013-Hypothalamus,
pubmed-meshheading:2854013-Natriuretic Agents,
pubmed-meshheading:2854013-Pituitary Gland, Anterior,
pubmed-meshheading:2854013-Sodium-Potassium-Exchanging ATPase
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pubmed:year |
1988
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pubmed:articleTitle |
Partial purification of a sodium pump inhibitor from bovine adenohypophysis. Its comparison with the natriuretic factor isolated from hypothalamus.
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pubmed:affiliation |
Dept. of Endocrinology, Ramón y Cajal Hospital, Madrid, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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