|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
1989-4-18
|
|
pubmed:abstractText |
Earlier we found that the immune response and antiviral protection from FMDV can be achieved by immunization with uncoupled FMDV peptides. In a search of approaches to animal protection from FMDV A22 strain we prepared a series of peptides corresponding to the putative antigenic determinants. Synthetic 131-149 and 140-149 sequences afforded 50 to 80% protection, both in the free state and conjugated with keyhole limpet hemocyanin. We believe that the 140-149 segment is so far the smallest peptide capable of eliciting specific antiviral protection without conjugation with a high molecular carrier.
|
|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0132-3423
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1363-71
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2852938-Animals,
pubmed-meshheading:2852938-Antigens, Viral,
pubmed-meshheading:2852938-Aphthovirus,
pubmed-meshheading:2852938-Chromatography, High Pressure Liquid,
pubmed-meshheading:2852938-Foot-and-Mouth Disease,
pubmed-meshheading:2852938-Guinea Pigs,
pubmed-meshheading:2852938-Peptides,
pubmed-meshheading:2852938-Viral Proteins,
pubmed-meshheading:2852938-Viral Structural Proteins,
pubmed-meshheading:2852938-Viral Vaccines
|
|
pubmed:year |
1988
|
|
pubmed:articleTitle |
[Antigenic structure of the foot-and-mouth disease virus. II. Synthesis of protective peptides from the major immunogenic region of VP1 protein of foot-and-mouth disease virus type A22].
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
